脂肪特异蛋白27（Fsp27）与脂肪代谢

doi:10.11843/j.issn.0366-6964.2014.03.002

畜牧兽医学报 ›› 2014, Vol. 45 ›› Issue (3): 347-353.doi: 10.11843/j.issn.0366-6964.2014.03.002

脂肪特异蛋白27（Fsp27）与脂肪代谢

潘洪彬^1,2，赵素梅²，孙泽威¹，龙国辉¹，高士争^2*，秦贵信^1*

(1.吉林农业大学动物科技学院，长春 130118； 2.云南农业大学物科技学院云南省动物营养与饲料重点实验室，昆明 650201)

收稿日期:2013-04-01 出版日期:2014-03-23 发布日期:2014-03-23
通讯作者: 高士争，教授，主要从事动物分子营养与代谢调控研究，E-mail：gaoszkm@126.com；秦贵信，教授，主要从事比较动物营养学和大豆抗营养因子研究，E-mail：guixin@public.cc.cn
作者简介:潘洪彬（1974-），男，吉林松原人，副教授，博士生,主要从事动物分子营养与代谢调控研究，E-mail:ynsdyz@163.com；赵素梅（1974-），女，河南周口人，教授，博士，主要从事动物分子营养与代谢调控研究，E-mail：xh_zsm@yahoo.com.cn。潘洪彬和赵素梅同为第一作者
基金资助:
国家自然科学基金（31160492）；云南省自然科学基金（2011FB052）；云南省教育厅基金（2011Y439）

Fat-specific Protein 27 (Fsp27) and Lipid Metabolism

PAN Hong-bin^1,2，ZHAO Su-mei²，SUN Ze-wei¹，LONG Guo-hui¹，GAO Shi-zheng^2*，QIN Gui-xin^1*

(1.College of Animal Science and Technology，Jilin Agricultural University，Changchun 130118, China；2.Key Laboratory of Animal Nutrition and Feed of Yunnan Province，College of Animal Science and Technology，Yunnan Agricultural University，Kunming 650201, China)

Received:2013-04-01 Online:2014-03-23 Published:2014-03-23

摘要/Abstract

摘要：

脂肪特异蛋白27（Fsp27）是一种新发现的定位在脂滴的蛋白质，在调控脂肪细胞内脂类贮存和线粒体活性方面起着重要作用。本文就Fsp27基因的发现、组织分布、促进脂滴生长机制、对脂肪代谢的影响和Fsp27的转录调控进行了综述，并进行了研究前景展望。可以确定，随着Fsp27研究的深入，其将在预防和治疗脂肪代谢紊乱相关疾病以及改善肉品质方面起到积极作用。

Abstract:

Fat-specific protein 27 (Fsp27)，localizing in the surface of lipid droplets(LDs),plays an important role in controlling lipid store and mitochondrial activity in adipocytes.The discovery of Fsp27 genes,tissue distribution，promoting the growth mechanism of LDs，the effect on fat metabolism and the transcriptional regulation of Fsp27 gene were reviewed in present paper.It is convincing that Fsp27 gene would play a positive role in the prophylactic and therapeutic treatment of lipid metabolic disorder disease and improving meat quality with the research advancing.

中图分类号:

S852.23

潘洪彬，赵素梅，孙泽威，龙国辉，高士争，秦贵信. 脂肪特异蛋白27（Fsp27）与脂肪代谢[J]. 畜牧兽医学报, 2014, 45(3): 347-353.

PAN Hong-bin，ZHAO Su-mei，SUN Ze-wei，LONG Guo-hui，GAO Shi-zheng，QIN Gui-xin. Fat-specific Protein 27 (Fsp27) and Lipid Metabolism[J]. ACTA VETERINARIA ET ZOOTECHNICA SINICA, 2014, 45(3): 347-353.

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脂肪特异蛋白27（Fsp27）与脂肪代谢

Fat-specific Protein 27 (Fsp27) and Lipid Metabolism

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